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Natural Moisturizing Factor (NMF)

The Natural Moisturizing Factor (NMF) is essential to SC barrier function and can be used to monitor biological
maturation processes occurring in epidermal cells.

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Corneocytes can be obtained from human subjects by tape stripping. ATR-FTIR imaging spectroscopy is used to evaluate relative differences in the NMF content, corneocyte hydration level and possibly lipid organization inside the SC.

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